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In Vitro Toxicology

Millicell Cell Culture Inserts

In vitro models play an important role in the toxicity testing of cosmetics, drugs and pharmaceutical therapies. Advancements in in vitro cell culture have given researchers a viable alternative and/or complement to live animal testing.

In vitro models offer a number of ethical and economic advantages over animal testing. These assays are being used earlier in toxicity testing pipelines, often to determine risk assessment and/or set up controls that will ultimately spare animal life. The combination of lower-cost and higher throughput assays can help bring products to market faster. Additionally, in vitro models give researchers an advantage in understanding the biological process involved in a toxic response sooner than if they were depending on the visual inspection of a live animal.

Millipore’s family of Millicell cell culture inserts and insert plates are widely used for in vitro toxicology testing. Additionally, Millipore offers a line of 96-well products for ADME and pre-ADME testing. In vitro assays supported include solubility as well as cell- and non-cell based drug absorption assays.

For more information on Millipore tools for in vitro toxicology testing, contact Millipore Technical Service at www.millipore.com/techservice

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