Milli-Q^® Ultrapure Water Purification Systems

Milli-Q® Ultrapure Water Purification Systems The standard for ultrapure water in the laboratory

New Features and Optional Accessories Add Control and Convenience
- Backlit display for easy access to system information
- Remote display for quality monitoring and operation up to 3 m (10') distance
- Ergonomically designed point-of-use dispense trigger for easier water delivery and fixed-volume water dispense
- The Milli-Q remote point-of-use dispenser for convenient delivery of ultrapure water up to 2.5 m (8') away from your Milli-Q system; can be wall-mounted, dispenser arm rotates 180° for total flexibility
- Foot pedal for hands-free water delivery from a Milli-Q system or remote POU dispenser
- Millipak Express 20 final filter for minimum ionic and organic contaminant release when used for sub-ppb analysis of volatile organics or endocrine disrupters
- Pyrogard^™ D UF filter reduces pyrogen levels in ultrapure water below 0.001 EU/mL and removes nucleases when connected to the outlet of a Milli-Q system


A Range of New Milli-Q Systems
Millipore has developed a range of Milli-Q ultrapure water systems designed to match specific water quality requirements. Each of the five new Milli-Q systems is designed to specifically target contaminants detrimental to particular applications such as HPLC, molecular biology and ICP-MS. The systems incorporate a high precision resistivity monitor that records conductivity or resistivity (compensated or not to 25 °C), and also feature a built-in TOC monitor with a 1 – 999 ppb detection range for accurate analysis of organics. Milli-Q resistivity and TOC meters are designed to take into account the suitability test requirements of USP 28-NF21. Validation and qualification services are available, and access to historical data via a computer interface is possible. All systems can be bench-operated, wall-mounted or bench-integrated for maximizing space requirements.



The Milli-Q Concept
Standard Purification Steps
All systems in the Milli-Q range employ a 3-step purification process:
Step 1:
Plug-in Q-Gard purification packs are tailored to the feedwater source to optimize the performance of downstream purification media to ensure consistent results.
Step 2:
Quantum application-specific cartridges remove ionic and organic contaminants down to trace levels.
Step 3:
Final purification of ultrapure water is carried out at the point-of-use by a pharmaceutical-grade, absolute 0.22 µm Millipak membrane filter that is recommended for most analytical applications.

Additional Purification Steps
UV Photo-oxidation:
The ultraviolet photo-oxidation process (UV at 254 and 185 nm) used in Milli -Q Gradient , Synthesis and Element Systems can effectively carry out the destruction of organic molecules, to reduce TOC levels to < 5 ppb, improving consistency and sensitivity in applications such as HPLC, IC, solid-phase extraction and UV spectroscopy.
Ultrafiltration:
Milli-Q Biocel and Synthesis Systems include a Pyrogard 5000 ultrafiltration cartridge for the production of pyrogen- and nuclease-free ultrapure water (<0.001  EU/mL), particularly important for life science or molecular biology applications.


Applications
- Milli-Q Academic System – General laboratory applications
- Milli-Q Gradient System – Analytical chemistry
- Milli-Q Biocel System – Life science applications
- Milli-Q Synthesis System – Molecular biology applications
- Milli-Q Element System – Ultratrace analysis


Features    (return to top)

Standard Academic A10 Gradient A10 Biocel A10 Synthesis A10 Element A10 Q-Gard™ cartridge • • • • • Quantum™ cartridge • • • • • Millipak Express 20 final filter • • • • • Optimizer™ LW Filter • Resistivity Meter • • • • • TOC Meter • • • • • UV Lamp (185//254 nm) • • • Pyrogard 5000 UF cartridge • • Volumetric Dispense • • • • • Backlit Display Panel • • • • • Remote Water Dispenser • Foot-pedal • Optional Academic A10 Gradient A10 Biocel A10 Synthesis A10 Element A10 Milli-Q Remote POU Water Dispenser • • • • Backlit Remote Display • • • • Foot-pedal • •     Pyrogard D final filter • • • • •

Product Water Specifications*   Academic A10 Gradient A10 Biocel A10 Synthesis A10 Element A10 Resistivity (MW·cm at 25 °C) 18.2 18.2   18.2 18.2 TOC (ppb) 5–10 1–5   2–5 <5 Pyrogens (EU/mL) NA NA < 0.001 < 0.001 NA Bacteria (cfu/mL) <1 <1   <1 <1 Flow Rate (L/min) 1.5 1.5   1 1.5 *    Typical values obtained with Elix feedwater; resistivity above 1 MW·cm and TOC <50 ppb, using Quantum EX and a new Millipak Express 20 final filter.

Feedwater Requirements Parameter Description / Specification Pressure Min 0.1 bar (1.5 psi) / Max 0.3 bar (4.5 psi) Flow rate Min 100 L /h Temperature Min 5 °C / Max 35 °C Connection 1/2 in. NPTM     Millipore recommends the use of pure (Type II or Type III) water produced by Elix® or RiOs™ systems to feed the Milli-Q system.

System Dimensions Height cm (in.) Width cm (in.) Depth cm (in.) Operating Weight kg (lb) Milli-Q Academic A10 45.7 (18) 25.5 (10) 31.5 (12.4)   Milli-Q Gradient A10 17.4 (38.4) Milli-Q Biocel A10 16.9 (37.3) Milli-Q Synthesis A10 16.9 (37.3) Milli-Q Element A10 18 (39.8)

Point-of-Use Dispenser Specifications    (return to top)
Materials
Non-wetted Surfaces
Arm: Polyamide with fiberglass
Base: Aluminum
Load: Stainless steel
Wetted Surfaces
Tubing: Polyethylene
Valve: Acrylonitrile butadiene styrene copolymer

Dimensions
Tubing:
2.5 m (8')
POU Dispenser, L x W x D:
13 cm x 6.98 cm x 3.81 cm
(5.1 in. x 2.7 in. x 1.5 in.)

Weight
1.65 kg (3.63 lb) dry
(without the load)
3 kg (6.61 lb)
with stainless steel load
Note: Point-of-Use dispenser flow rate may be slightly less than system flow rate.

Milli-Q Academic System

Milli-Q Gradient System

Milli-Q Biocel System

Milli-Q Synthesis System

Milli-Q Element System