Prostak Ultrafiltration Modules

Prostak Ultrafiltration Modules

Description
Prostak UF modules and systems are designed for concentrating and diafiltering biological macromolecules in validated separation processes that must satisfy current Good Manufacturing Practices. Prostak UF also has broad solvent resistant capabilities.

A complete line of bench-top, pilot and process-scale standard and custom Prostak systems is available for pharmaceutical product and process development, scale-up and production.


Typical Applications
- Concentration of, buffer exchange of, and solvent removal from: – Recombinant proteins – Hormones – Monoclonal antibodies – Blood and plasma fractions – Viruses – Bacterial toxins and toxoids – Protein and polysaccharide antigens – Large peptides
- Depyrogenation of solutes and solvents smaller than 3 kDaltons


Dimensions

4-Stack 10-Stack 20-stack Weight, kg (lbs) 1.45 (3.2) 2.3 (5.0) 3.7 (8.0) Length, cm (in) 39.4 (15.5) 39.4 (15.5) 39.4 (15.5) Width, cm (in) 19 (7.5) 19 (7.5) 19 (7.5) Height, cm (in) 5 (2.0) 7 (2.7) 10 (4.0) Internal Volume Total, mL 530 950 1650 Feed Side, mL 340 625 1100 Filtrate Side, mL 190 325 550 Membrane Area, m2 (ft2) 0.39 0.93 1.9

Specifications    (return to top)

Materials of Construction PT Membrane Polyethersulfone PL Membrane Regenerated cellulose Plate Polypropylene Maximum Inlet Pressure   5.6 bar (80 psi) Maximum Temperature °C   55 Maximum Transmembrane Pressure - Forward   5.6 bar (80 psi) pH Range - Intermittent (up to 250 h) PT Series 1–14 PL Series 2–14 pH Range - continuous PT Series 2–14 PL Series 2–13 Prefiltration Required   100 µm