Millipore - Product Module

Sterilizing-grade Durapore 0.1 µm and 0.22 µm Hydrophilic Cartridge Filters

Description
A trusted name in the industry for over 25 years, Durapore^® sterilizing-grade 0.1 µm and 0.22 µm hydrophilic polyvinylidene fluoride (PVDF) membranes are low protein binding* and provide sterility assurance, high flow rates and throughputs. The Durapore membrane contributes to clean processes due to low extractables, broad chemical compatibility, and its non-fiber releasing properties.

Hydrophilic Durapore cartridge filters provide high throughput with minimal differential pressure. Cartridges are robust, strong, resilient and are designed to withstand multiple steam-in-place cycles. Each Durapore cartridge filter is integrity tested during the manufacturing process.

Regulatory Compliance
Filters with hydrophilic Durapore membrane are designed, developed, and manufactured in accordance with a Quality Management System approved by an accredited registering body to an ISO^® 9000 Quality Systems Standard and are shipped with a Certificate of Quality. Each cartridge filter is integrity tested during manufacturing and is supported by a Validation Guide for compliance with regulatory requirements.

For traceability and easy identification, each device is marked with the product name and identifying characteristics.

Multiple Formats Available
A full range of filtration areas is available to suit varying application requirements and a variety of connection options are offered to meet your application and housing requirements.

Specifications (return to top)

Per 10-inch Cartridge
Materials of Construction
Filter media
Hydrophilic PVDF
Supports
Polypropylene
Structural components
Polypropylene
O-rings
Silicone O-rings
Filtration Area, m²
0.69
Integrity Test, Bubble Point
0.1 µm
≥4830 mbar (70 psig) air with water
0.22 µm
≥3450 mbar (50 psig) air with water
Integrity Test, Air Diffusion
0.1 µm
≤20 mL/min @ 3.9 bar (56 psig) in water
0.22 µm
≤13.3 mL/min @ 2.8 bar (40 psig) in water
Maximum Differential Pressure, bar (psid)
Forward - 5.5 (80) @ 25 °C; 1.7 (25) @ 80 °C; 0.35 (5) @ 135 °C; Reverse - 3.5 (50) @ 25 °C
NVR Gravimetric Extractables
≤20 mg after 24-h soak in water
Oxidizable Substances
Will meet the USP Oxidizable Substances Test requirements after a water flush of ≤1 L

Bacterial Endotoxins
<0.5 EU/mL as determined by the LAL test
Bacterial Retention
Quantitative retention of 10⁷ CFU/cm² Brevundimonas diminuta ATCC^® 19146 per ASTM methodology.
Sterilization
30 SIP cycles of 30 min @ 135 °C; 30 autoclave cycles of 60 min @ 126 °C
Toxicity
Component materials meet the criteria of the USP <88> Reactivity Test for Class VI Plastics. These products meet the requirements of the USP <88> Safety Test, utilizing a 0.9% sodium chloride extraction.
Good Manufacturing Practices
These products are manufactured in a facility which adheres to FDA Device Good Manufacturing Practices.
Non-fiber Releasing
Component materials meet the "non-fiber releasing" criteria as defined in 21 CFR 210.3 (b) (6).
Indirect Food Additive
All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177–182.

Typical Clean Water Flow Rate vs Pressure Drop

Cartridge Filters with 0.1 µm Hydrophilic Durapore (CVVL)

Cartridge Filters with 0.22 µm Hydrophilic Durapore (CVGL)

Compare	Catalogue No.	Cartridge Nominal Length, in (cm)
	CVGL01TP3	10 (25)	» Add to Cart
	CVGL02TP3	20 (50)	» Add to Cart
	CVGL03TP3	30 (75)	» Add to Cart

Compare	Catalogue No.	Cartridge Nominal Length, in (cm)
	CVGL51TP3	10 (25)	» Add to Cart
	CVGL52TP3	20 (50)	» Add to Cart
	CVGL53TP3	30 (75)	» Add to Cart

Compare	Catalogue No.	Cartridge Nominal Length, in (cm)
	CVGL75S01	5 (12.5)	» Add to Cart
	CVGL71TP3	10 (25)	» Add to Cart
	CVGL72TP3	20 (50)	» Add to Cart
	CVGL73TP3	30 (75)	» Add to Cart
	CVGL74TP3	40 (100)	» Add to Cart

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