Ordering Information
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Western Blot Analysis:
NMDAR1C was detected at 1:2000 dilution in 10 µg of rat brain tissue Lysate.
Anti-NMDAR1C
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| R | WB | null | Affinity Purified | Polyclonal Antibody |
UniProt Number:
Description:
Anti-NMDAR1C
Background Information:
NMDA receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long term potentiation, an activity dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2B may be a candidate gene for the neurodegenerative disorder dentato-rubro-pallidoluysian atrophy (DRPLA).
Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage dependent Mg2+ blockade and high Ca2+ permeability. The involvement of NMDAR in the CNS has become a focus area for neurodegenerative diseases such as Alzheimer's disease and also epilepsy and ischemic neuronal cell death.
Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage dependent Mg2+ blockade and high Ca2+ permeability. The involvement of NMDAR in the CNS has become a focus area for neurodegenerative diseases such as Alzheimer's disease and also epilepsy and ischemic neuronal cell death.
Specificity:
Cat. # AB15382 recognizes C-Terminus of NMDAR1C.
Key Applications:
Western Blotting
Application Notes:
NMDAR1C was detected at 1:2000 dilution in 10 µg of rat brain tissue Lysate.
Species Reactivity:
Rat
Species Reactivity Note:
Reactivity with other species has not been tested.
Immunogen:
Synthetic Linear Peptide.
Molecular Weight:
120 kDa
Control:
rat brain lysate
Presentation:
Purified in PBS with 0.05% NaN3
Storage Conditions:
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Quality Assurance:
Routinely evaluated by immunoblot.
Antibody Category:
Neuroscience
Antibody Sub-Category:
Neurotransmitters & Receptors
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Descriptive Text:
Trade Name:
Chemicon (Millipore)
Format:
Affinity Purified
Antibody Type:
Polyclonal Antibody