Anti-NECL-1
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| M | IH, WB | Rabbit | Affinity Purified | Polyclonal Antibody |
UniProt Number:
Description:
Anti-NECL-1
Background Information:
Nectins are immunoglobulin superfamily adhesion molecules that participate in the organization of epithelial and endothelial junctions. Human and mouse NECL1 share 87.3% identity at the amino acid level (1). NECL1 contains an ectodomain made of three immunoglobulin-like domains, and a cytoplasmic region homologous to those of glycophorin C and contactin-associated protein. NECL1 predominantly expressed in the central nervous system, mainly in neuronal cell bodies in a variety of brain regions including the cerebellum, cerebral cortex and hippocampus. NECL1 localizes to the cell-cell junctions and recruits protein 4.1N to the plasma membranes through its C-terminus, thus may regulate the function of the cell-cell junction.
Specificity:
NECL-1
Key Applications:
- Immunohistochemistry
- Western Blotting
Application Notes:
Western Blot Analysis: NECL-1 can be detected at 1/500 dilution. Testing at further dilution was not conducted.
Immunohistochemistry: 1:50 to 1:1000 straight dilution of Cat. # AB15301 was tested on human medulla oblongata tissue.
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: 1:50 to 1:1000 straight dilution of Cat. # AB15301 was tested on human medulla oblongata tissue.
Optimal working dilutions must be determined by the end user.
Species Reactivity:
Mouse
Immunogen:
Synthetic Peptide
Molecular Weight:
43 kDa
Control:
Tested on Adult mouse brain lysate
Presentation:
Purified Antibody in PBS with 0.1% NaN3
Storage Conditions:
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Gene Symbol:
- CADM3
- IGSF4B
- NECL1
- SYNCAM3
- TSLL1
Antibody Category:
Neuroscience
Antibody Sub-Category:
Neurofilament & Neuron Metabolism
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Purification Method:
Immuno Affinity Purified
Format:
Affinity Purified
Antibody Type:
Polyclonal Antibody
Host:
Rabbit