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IB: COS transfected cell lysate was probed with anti-Myc Tag, clone 4A6, HRP conjugate (1:5000 dilution).
Anti-Myc Tag, clone 4A6, HRP conjugate
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | WB | Mouse | Purified | Monoclonal Antibody |
UniProt Number:
UniProt Summary
FUNCTION: SwissProt: P01106 # Participates in the regulation of gene transcription. Binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.
SIZE: 439 amino acids; 48804 Da
SUBUNIT: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with TAF1C and SPAG9. Interacts with PARP10. Interact ... see more »
SIZE: 439 amino acids; 48804 Da
SUBUNIT: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with TAF1C and SPAG9. Interacts with PARP10. Interact ... see more »
Entrez Gene Number:
Entrez Gene Summary
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation ini
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Description:
Anti-Myc Tag, clone 4A6, HRP conjugate
Clone:
4A6
Specificity:
Recognizes and is specific for recombinant proteins containing the Myc epitope tag (EQKLISEEDL) in a variety of sequence contexts. Also recognizes human Myc.
Key Applications:
Western Blotting
Species Reactivity:
Human
Immunogen:
KLH-conjugated, synthetic peptide corresponding to amino acids 410-420 (MEQKLISEEDL) of human Myc.
Control:
Positive control for human Myc: Widespread expression including A431 cell lysate, ovarian cancer cell lysate, or breast carcinoma tissue. Myc fusion protein expressed in cells.
Presentation:
PBS with 0.05% Kathon™ and 0.2mg/ml BSA prior to the addition of glycerol to 50%
Storage Conditions:
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Gene Symbol:
- MYC
- C-MYC
- c-Myc
Quality Assurance:
routinely evaluated in western blot to detect Myc-tagged recombinant protein
Antibody Category:
Epitope Tags & General Use
Antibody Sub-Category:
Epitope Tags
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Descriptive Text:
Concentration:
Variable
Format Code:
Pur
Trade Name:
Upstate (Millipore)
Purification Method:
Protein A Purified
Format:
Purified
Product Overview:
Immunogen: peptide corresponding to amino acids 410-420 (MEQKLISEEDL) of human Myc
Specificity: Recognizes and is specific for recombinant proteins containing the Myc epitope tag (EQKLISEEDL) in a variety of sequence contexts. Also recognizes human Myc.
Species Cross-reactivity: Human, others not tested
Ig Type: IgG
Host: Mouse
Molecular Weight: Varies depending upon the protein which is tagged
Specificity: Recognizes and is specific for recombinant proteins containing the Myc epitope tag (EQKLISEEDL) in a variety of sequence contexts. Also recognizes human Myc.
Species Cross-reactivity: Human, others not tested
Ig Type: IgG
Host: Mouse
Molecular Weight: Varies depending upon the protein which is tagged
Antibody Type:
Monoclonal Antibody
Host:
Mouse